(Phys.org) —Sustained-release formulations that release drugs over longer periods of time are not the final step in the evolution of "intelligent" drug delivery systems. Modern pharmaceuticals are being designed to be released only in a specific, diseased organ; on cues from our circadian rhythm; or under specific physiological conditions. In the journal Angewandte Chemie, a team of American and Korean researchers has now introduced "microbottles" with "corks" that release their contents only when the temperature rises above a defined level.
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